Raising a heterologous tier 2 neutralizing antibody (nAb) response stays a daunting job for HIV vaccine growth. In this research, we explored the utility of numerous HIV-1 envelope (Env) immunogens in a sequential immunization scheme as a answer to this job. This exploration stemmed from the rationale that gp145, a membrane-bound truncation kind of HIV Env, could facilitate the focusing of induced antibody response on neutralizing epitopes when sequentially mixed with the soluble gp140 kind as immunogens in a prime-boost mode. We first confirmed that gp140 DNA prime-gp145 Tiantan vaccinia (TV) enhance probably represents a common format for inducing potent nAb response in mice.
However, when examined in rhesus macaque, this modality confirmed little effectiveness. To enhance the efficacy, we prolonged the unique modality by including a robust protein enhance, particularly native-like SOSIP.664 trimer displayed on ferritin-based nanoparticle (NP), which was generated by a newly developed click on method. The ensuing three-immunization routine succeeded in eliciting tier-2 nAb response with substantial breadth when carried out in rhesus macaque over a brief 8-week schedule. Importantly, the elicited nAb response was in a position to successfully comprise viremia upon a heterologous SHIV problem. Collectively, our research highlighted that diversification of Env immunogens, in each varieties and formulations, underneath the framework of a sequential immunization scheme would possibly open new alternative towards HIV vaccine growth.
An efficacious HIV-1 vaccine has remained an elusive goal for nearly 40 years. The sheer variety of the virus is one of the most important roadblocks for vaccine growth. HIV-1 often mutates and numerous strains predominate in numerous geographic areas, making the event of a globally relevant vaccine extraordinarily troublesome. Multiple approaches have been taken to overcome the problem of viral variety, together with sequence optimization, growth of consensus and mosaic sequences and the use of totally different prime-boost approaches. To develop an efficacious vaccine, these approaches may have to be mixed. One method to probably synergize these approaches is to use a rationally designed protein nanoparticle that enables for the native-like presentation of antigens, such because the self-assembling protein nanoparticle.
Parainfluenza Virus 5 Priming Followed by SIV/HIV Virus-Like-Particle Boosting Induces Potent and Durable Immune Responses in Nonhuman Primates
The seek for a preventive vaccine towards HIV an infection stays an ongoing problem, indicating the necessity for novel approaches. Parainfluenza virus 5 (PIV5) is a paramyxovirus replicating within the higher airways that isn’t related with any animal or human pathology. In animal fashions, PIV5-vectored vaccines have proven safety towards influenza, RSV, and different human pathogens. Here, we generated PIV5 vaccines expressing HIV envelope (Env) and SIV Gag and administered them intranasally to macaques, adopted by boosting with virus-like particles (VLPs) containing trimeric HIV Env. Moreover, we in contrast the immune responses generated by PIV5-SHIV prime/VLPs enhance routine in naïve vs a management group wherein pre-existing immunity to the PIV5 vector was established.
We display for the primary time that intranasal administration of PIV5-based HIV vaccines is protected, well-tolerated and immunogenic, and that boosting with adjuvanted trimeric Env VLPs enhances humoral and mobile immune responses. The PIV5 prime/VLPs enhance routine induced strong and sturdy systemic and mucosal Env-specific antibody titers with practical actions together with ADCC and neutralization. This routine additionally induced extremely polyfunctional antigen-specific T cell responses. Importantly, we present that diminished responses due to PIV5 pre-existing immunity may be overcome partly with VLP protein boosts.
Overall, these outcomes set up that PIV5-based HIV vaccine candidates are promising and warrant additional investigation together with transferring on to primate problem research. This blended strategies research aimed to consider the feasibility and preliminary efficacy of a totally automated, interactive smartphone-delivered intervention for smoking cessation amongst individuals dwelling with HIV in Cambodia. We used the explanatory sequential design, with a pilot two-group single-blind randomized managed trial (N = 50) adopted by in-depth interviews with all trial individuals. In the trial, individuals had been randomized to Standard Care (SC) or Automated Messaging (AM) group. SC comprised temporary recommendation to give up and self-help supplies.

Exploring HIV stigma amongst future healthcare suppliers in Indonesia
Future healthcare professionals are an vital group for interventions to get rid of HIV stigma within the well being workforce. Researchers examined HIV stigma and its relationship with healthcare self-discipline, HIV information, and religiosity amongst nursing, medical, and midwifery college students (N = 505) in three areas of Indonesia. In a multivariable linear mannequin, larger HIV stigma was related with male intercourse, decrease ranges of earnings and HIV information, and better ranges of religiosity. An interplay of healthcare self-discipline and province was additionally important. Medical college students in Jakarta had larger predicted stigma scores in contrast to nursing college students in Jakarta and in contrast to medical college students in different provinces.
Nursing college students in Papua had decrease predicted stigma scores in contrast to medical and midwifery college students in Papua and in contrast to nursing college students elsewhere. Strategies to cut back HIV stigma within the Indonesian well being workforce ought to embrace a robust deal with pre-clinical academic settings and contemplate public nursing establishments as offering attainable greatest apply fashions. Human immunodeficiency virus sort 1 (HIV-1) is principally transmitted by sexual activity, and efficient microbicides stopping HIV-1 transmission are nonetheless required.
Recombinant HIV-1 Envelope, His Tag |
7-07590 |
CHI Scientific |
1000µg |
Ask for price |
Recombinant HIV-1 Envelope (233) |
7-07585 |
CHI Scientific |
100µg |
Ask for price |
Recombinant HIV-1 Envelope (233) |
7-07586 |
CHI Scientific |
500µg |
Ask for price |
Recombinant HIV-1 Envelope (233) |
7-07587 |
CHI Scientific |
1000µg |
Ask for price |
HIV 1 envelope recombinant antigen |
00176-V-01mg |
Virogen |
0,1 mg |
EUR 267.5 |
|
Description: HIV 1 envelope recombinant antigen. HIV-1 evnelope protein spanning the C-Terminus of gp 120 and most of gp 41. |
HIV 1 envelope recombinant antigen |
00176-V-1000ug |
Virogen |
1000 ug |
EUR 1282.5 |
|
Description: HIV 1 envelope recombinant antigen. HIV-1 evnelope protein spanning the C-Terminus of gp 120 and most of gp 41. |
Recombinant HIV-2 Envelope |
7-07746 |
CHI Scientific |
1000µg |
Ask for price |
Recombinant HIV-1 p24 His Tag |
7-07606 |
CHI Scientific |
5µg |
Ask for price |
Recombinant HIV-1 p24 His Tag |
7-07607 |
CHI Scientific |
20µg |
Ask for price |
Recombinant HIV-1 p24 His Tag |
7-07608 |
CHI Scientific |
1mg |
Ask for price |
Recombinant HIV-1 gp41, His tag |
7-07627 |
CHI Scientific |
100µg |
Ask for price |
Recombinant HIV-1 gp41, His tag |
7-07628 |
CHI Scientific |
500µg |
Ask for price |
Recombinant HIV-1 gp41, His tag |
7-07629 |
CHI Scientific |
1000µg |
Ask for price |
HIV 1, 2 envelope recombinant antigen |
00175-V-01mg |
Virogen |
0,1 mg |
EUR 267.5 |
|
Description: HIV 1, 2 envelope recombinant antigen. HIV-1 envelope conjugated to HIV-2 envelope peptide. |
HIV 1, 2 envelope recombinant antigen |
00175-V-1000ug |
Virogen |
1000 ug |
EUR 1282.5 |
|
Description: HIV 1, 2 envelope recombinant antigen. HIV-1 envelope conjugated to HIV-2 envelope peptide. |
Recombinant HIV-1 Envelope conjugated to HIV-2 gp39 |
7-07711 |
CHI Scientific |
100µg |
Ask for price |
Recombinant HIV-1 Envelope conjugated to HIV-2 gp39 |
7-07712 |
CHI Scientific |
500µg |
Ask for price |
Recombinant HIV-1 Envelope conjugated to HIV-2 gp39 |
7-07713 |
CHI Scientific |
1000µg |
Ask for price |
Recombinant HIV Type-O Envelope |
7-07714 |
CHI Scientific |
100µg |
Ask for price |
Recombinant HIV Type-O Envelope |
7-07715 |
CHI Scientific |
500µg |
Ask for price |
Recombinant HIV Type-O Envelope |
7-07716 |
CHI Scientific |
1000µg |
Ask for price |
Recombinant HIV-1 p24 gag, His Tag |
7-07609 |
CHI Scientific |
100µg |
Ask for price |
Recombinant HIV-1 p24 gag, His Tag |
7-07610 |
CHI Scientific |
500µg |
Ask for price |
Recombinant HIV-1 p24 gag, His Tag |
7-07611 |
CHI Scientific |
1000µg |
Ask for price |
HIV-1 gp41, His tag |
E410A25-10 |
EnoGene |
10μg |
EUR 694 |
HIV-1 p24, His tag |
E410A26-20 |
EnoGene |
20μg |
EUR 434 |
Recombinant HIV-1 gp 41 Envelope Protein |
VAng-0532Lsx-inquire |
Creative Biolabs |
inquire |
Ask for price |
Description: HIV type 1 Glycoprotein 41 Envelope Antigen, recombinant protein from E. coli, MW 146 kDa with Beta-galactosidase (114 kDa), 1.00 mg/mL. |
HIV-1 Envelope (233) Protein |
20-abx260140 |
Abbexa |
-
EUR 885.00
-
EUR 342.00
-
EUR 1372.00
|
|
|
HIV 1 Envelope gp41 Protein |
abx060584-05mg |
Abbexa |
0.5 mg |
EUR 940 |
|
HIV 1 Envelope gp41 Protein |
abx060585-100ug |
Abbexa |
100 ug |
EUR 1080 |
|
Recombinant (E.Coli) HIV-1 Envelope conjugated to HIV-2 gp39 |
RP-564 |
Alpha Diagnostics |
100 ug |
EUR 286 |
Recombinant HIV-2 gp36, His Tag |
7-07738 |
CHI Scientific |
100µg |
Ask for price |
Recombinant HIV-2 gp36, His Tag |
7-07739 |
CHI Scientific |
500µg |
Ask for price |
Recombinant HIV-2 gp36, His Tag |
7-07740 |
CHI Scientific |
1000µg |
Ask for price |
Recombinant Zika Envelope Protein, His, E.coli-100ug |
QP13997-HIS-100ug |
EnQuireBio |
100ug |
EUR 218 |
Recombinant Zika Envelope Protein, His, E.coli-10ug |
QP13997-HIS-10ug |
EnQuireBio |
10ug |
EUR 201 |
Recombinant Zika Envelope Protein, His, E.coli-1mg |
QP13997-HIS-1mg |
EnQuireBio |
1mg |
EUR 1261 |
Recombinant Zika Envelope Protein, His, E.coli-2ug |
QP13997-HIS-2ug |
EnQuireBio |
2ug |
EUR 155 |
Recombinant Zika Envelope Protein, His, E.coli-500ug |
QP13997-HIS-500ug |
EnQuireBio |
500ug |
EUR 663 |
Recombinant Zika Envelope Protein, His, E.coli-50ug |
QP13997-HIS-50ug |
EnQuireBio |
50ug |
EUR 545 |
Recombinant (E.Coli, His-tag) HIV-1 pol Integrase |
RP-555 |
Alpha Diagnostics |
10 ug |
EUR 164 |
Recombinant (E.Coli, His-tag)HIV-1 p31 Integrase |
RP-579 |
Alpha Diagnostics |
2 ug |
EUR 164 |
Recombinant HIV-1 gp41, MBP tag |
7-07630 |
CHI Scientific |
100µg |
Ask for price |
Recombinant HIV-1 gp41, MBP tag |
7-07631 |
CHI Scientific |
500µg |
Ask for price |
Recombinant HIV-1 gp41, MBP tag |
7-07632 |
CHI Scientific |
1000µg |
Ask for price |
Recombinant HIV-1 Envelope Protein, Untagged, E.coli-100ug |
QP12241-100ug |
EnQuireBio |
100ug |
EUR 218 |
Recombinant HIV-1 Envelope Protein, Untagged, E.coli-1mg |
QP12241-1mg |
EnQuireBio |
1mg |
EUR 1061 |
Recombinant HIV-1 Envelope Protein, Untagged, E.coli-500ug |
QP12241-500ug |
EnQuireBio |
500ug |
EUR 663 |
HIV-2 Envelope Protein |
20-abx260147 |
Abbexa |
-
EUR 885.00
-
EUR 342.00
-
EUR 1372.00
|
|
|
HIV 2 Envelope Protein |
abx060590-1mg |
Abbexa |
1 mg |
EUR 1574 |
|
HIV-1 Envelope conjugated to HIV-2 gp39 Protein |
20-abx260144 |
Abbexa |
-
EUR 885.00
-
EUR 342.00
-
EUR 1372.00
|
|
|
Recombinant (E.Coli, His-tag) HIV-1 gp120 nef Mosaic |
RP-534 |
Alpha Diagnostics |
100 ug |
EUR 286 |
Recombinant HIV HTLV-1 Envelope Protein, Untagged, E.coli-100ug |
QP12353-100ug |
EnQuireBio |
100ug |
EUR 218 |
Recombinant HIV HTLV-1 Envelope Protein, Untagged, E.coli-1mg |
QP12353-1mg |
EnQuireBio |
1mg |
EUR 1061 |
Recombinant HIV HTLV-1 Envelope Protein, Untagged, E.coli-500ug |
QP12353-500ug |
EnQuireBio |
500ug |
EUR 663 |
Recombinant HIV-2 gp36 Protein, His, E.coli-100ug |
QP12269-HIS-100ug |
EnQuireBio |
100ug |
EUR 201 |
Recombinant HIV-2 gp36 Protein, His, E.coli-1mg |
QP12269-HIS-1mg |
EnQuireBio |
1mg |
EUR 663 |
Recombinant HIV-2 gp36 Protein, His, E.coli-500ug |
QP12269-HIS-500ug |
EnQuireBio |
500ug |
EUR 463 |
HIV Type-O Envelope Protein |
20-abx260145 |
Abbexa |
-
EUR 885.00
-
EUR 342.00
-
EUR 1372.00
|
|
|
HIV 2 Envelope gp36 Protein |
abx060591-1mg |
Abbexa |
1 mg |
EUR 1358 |
|
HIV 2 Envelope gp36 Protein |
abx060592-100ug |
Abbexa |
100 ug |
EUR 1066 |
|
HIV type O envelope antigen |
00178-V-01mg |
Virogen |
0,1 mg |
EUR 267.5 |
|
Description: HIV type O envelope antigen. Synthetic HIV type-O peptide, containing the HIV type-O envelope-derived sequence. |
HIV type O envelope antigen |
00178-V-1000ug |
Virogen |
1000 ug |
EUR 1282.5 |
|
Description: HIV type O envelope antigen. Synthetic HIV type-O peptide, containing the HIV type-O envelope-derived sequence. |
HIV 2 gp36 envelope antigen |
00180-V-01mg |
Virogen |
0,1 mg |
EUR 267.5 |
|
Description: HIV 2 gp36 envelope antigen. Synthetic HIV-2 Peptide containing the HIV-2 specific sequence of gp36. |
HIV 2 gp36 envelope antigen |
00180-V-1000ug |
Virogen |
1000 ug |
EUR 1282.5 |
|
Description: HIV 2 gp36 envelope antigen. Synthetic HIV-2 Peptide containing the HIV-2 specific sequence of gp36. |
Recombinant HIV-2 Envelope Protein, Untagged, E.coli-100ug |
QP12267-100ug |
EnQuireBio |
100ug |
EUR 218 |
Recombinant HIV-2 Envelope Protein, Untagged, E.coli-1mg |
QP12267-1mg |
EnQuireBio |
1mg |
EUR 1061 |
Recombinant HIV-2 Envelope Protein, Untagged, E.coli-500ug |
QP12267-500ug |
EnQuireBio |
500ug |
EUR 663 |
HCC-1 (CCL14) Human Recombinant Protein, His Tag |
PROTQ16627-1 |
BosterBio |
Regular: 10ug |
EUR 317 |
Description: HCC-1 Human Recombinant fused with a 21 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 95 amino acids (20-93 a.a.) and having a molecular mass of 10.9kDa. The HCC-1 is purified by proprietary chromatographic techniques. |
Recombinant HIV-2 gp36, MBP tag |
7-07735 |
CHI Scientific |
100µg |
Ask for price |
Recombinant HIV-2 gp36, MBP tag |
7-07736 |
CHI Scientific |
500µg |
Ask for price |
Recombinant HIV-2 gp36, MBP tag |
7-07737 |
CHI Scientific |
1000µg |
Ask for price |
Visfatin Recombinant Protein Human, His Tag |
PROTP43490-1 |
BosterBio |
Regular: 25ug |
EUR 317 |
Description: Visfatin Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 511 amino acids and having a molecular mass of 57 kDa. ;The recombinant human Visfatin is fused to His tag at N-Terminus. |
TXN1, Thioredoxin Recombinant Protein, His Tag |
PROTP0AA25-1 |
BosterBio |
Regular: 10ug |
EUR 317 |
Description: Recombinant Thioredoxin produced in E.Coli is a single, non-glycosylated polypeptide chain containing 119 amino acids (2-109 a.a.) and having a molecular mass of 12.9kDa. TRX contains an amino acid His Tag N-terminus and is purified by proprietary chromatographic techniques. |
Streptavidin, Streptavidin Recombinant Protein, His Tag |
PROTP22629-1 |
BosterBio |
Regular: 20ug |
EUR 317 |
Description: Recombinant Streptomyces Avidinii Streptavidin produced in E.Coli is a single, non-glycosylated polypeptide chain (25-183) containing a total of 167 amino acids and having a molecular mass of 17kDa. The Streptavidin protein is fused to an 8 aa N-terminal His-Tag and purified by proprietary chromatographic techniques. |
C5a (His-Tag), murine recombinant protein |
P1112-.1 |
ApexBio |
100 µg |
EUR 962 |
Description: Mouse complement C5a is a 77-amino acid peptide and is generated during complement activation from the ?-chain of complement C5. Its molecular mass is 9 kDa. Mouse C5a shares 60% and 82% amino acid sequence identity to human C5a and rat C5a, respectively |
C5a (His-Tag), murine recombinant protein |
P1112-1 |
ApexBio |
1 mg |
EUR 6940 |
Description: Mouse complement C5a is a 77-amino acid peptide and is generated during complement activation from the ?-chain of complement C5. Its molecular mass is 9 kDa. Mouse C5a shares 60% and 82% amino acid sequence identity to human C5a and rat C5a, respectively |
Human, LAG-1 (CCL4L1) Human Recombinant Protein, His Tag |
PROTQ8NHW4-1 |
BosterBio |
Regular: 20ug |
EUR 317 |
Description: LAG-1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 94 amino acids (24-92 a.a.) and having a molecular mass of 10.5kDa (Molecular weight on SDS-PAGE will appear higher).;LAG-1 is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
NRN1 Human, Neuritin-1 Human Recombinant Protein, His Tag |
PROTQ9NPD7-1 |
BosterBio |
Regular: 10ug |
EUR 317 |
Description: Neuritin-1 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain (Ala28-Gly116) containing 99 amino acids including a 10 aa His tag at N-terminus. The total calculated molecular mass is 11.02kDa. |
KLK1 Human, Kallikrein-1 Human Recombinant Protein, His Tag |
PROTP06870-1 |
BosterBio |
Regular: 10ug |
EUR 317 |
Description: Kallikrein-1 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 259 amino acids (25-262) and having a molecular mass of 28.7kDa.;KLK1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
Envelope-1, Dengue Virus Subtype 1 Recombinant Protein, Insect Cells |
PROTB1PNJ5-1 |
BosterBio |
Regular: 10ug |
EUR 317 |
Description: Recombinant Dengue Virus Subtype 1 produced in Insect Cells is a polypeptide chain containing amino acids 281-675 and having a molecular weight of approximately 50kDa. ;Dengue Envelope-1 is purified by proprietary chromatographic technique. |
Recombinant HIV Type-O Envelope Protein, Untagged, E.coli-100ug |
QP12237-100ug |
EnQuireBio |
100ug |
EUR 218 |
Recombinant HIV Type-O Envelope Protein, Untagged, E.coli-1mg |
QP12237-1mg |
EnQuireBio |
1mg |
EUR 1061 |
Recombinant HIV Type-O Envelope Protein, Untagged, E.coli-500ug |
QP12237-500ug |
EnQuireBio |
500ug |
EUR 663 |
IL-1-alpha Interleukin-1 alpha Mouse Recombinant Protein, His Tag |
PROTP01582-1 |
BosterBio |
Regular: 20ug |
EUR 317 |
Description: IL 1 alpha Mouse Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 179 amino acids (115-270 a.a) and having a molecular mass of 20.4kDa.;IL 1 alpha is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
IL-1-alpha Interleukin-1 alpha Human Recombinant Protein, His Tag |
PROTP01583-1 |
BosterBio |
Regular: 20ug |
EUR 317 |
Description: IL-1A Human Recombinant produced in E.Coli is single, a non-glycosylated, Polypeptide chain containing 159 amino acids fragment (113-271) with an amino-terminal hexahistidine tag and having a total molecular mass of 22.5kDa. ;The Interleukin-1 alpha His-tag is purified by proprietary chromatographic techniques. |
IL-1-beta Interleukin-1 beta Mouse Recombinant Protein, His Tag |
PROTP10749-1 |
BosterBio |
Regular: 25ug |
EUR 317 |
Description: Interleukin-1 beta Mouse Recombinant produced in E.Coli is a non-glycosylated, Polypeptide chain containing 189 amino acids and having a molecular mass of 21 kDa. ;The IL-1b is fused to His-Tag and purified by proprietary chromatographic techniques. |
IL-1-alpha Interleukin-1 alpha Rat Recombinant Protein, His Tag |
PROTP16598-1 |
BosterBio |
Regular: 20ug |
EUR 317 |
Description: IL 1 alpha Rat Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 179 amino acids (115-270 a.a) and having a molecular mass of 20.2kDa. |
Recombinant HIV Type-O gp41, MBP tag |
7-07720 |
CHI Scientific |
100µg |
Ask for price |
Recombinant HIV Type-O gp41, MBP tag |
7-07721 |
CHI Scientific |
500µg |
Ask for price |
Recombinant HIV Type-O gp41, MBP tag |
7-07722 |
CHI Scientific |
1000µg |
Ask for price |
Recombinant HTLV-1 Envelope |
7-07753 |
CHI Scientific |
100µg |
Ask for price |
Recombinant HTLV-1 Envelope |
7-07754 |
CHI Scientific |
500µg |
Ask for price |
Recombinant HTLV-1 Envelope |
7-07755 |
CHI Scientific |
1000µg |
Ask for price |
TFF1 Human, Trefoil Factor-1 Human Recombinant Protein, His Tag |
PROTP04155-1 |
BosterBio |
Regular: 20ug |
EUR 317 |
Description: TFF-1 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 70 amino acids (25-84) which includes a 10 amino acid His Tag and having a total molecular mass of 7.9 kDa. ;TFF-1 Human Recombinant is purified by proprietary chromatographic techniques. |
Human, Leptin Human Recombinant Protein, His Tag |
PROTP41159-1 |
BosterBio |
Regular: 25ug |
EUR 317 |
Description: Leptin Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing amino acids 48-167 and having a total molecular mass of 19 kDa including the 4 kDa His tag.;The Leptin is purified by proprietary chromatographic techniques. |
Enteropeptidase/ Enterokinase Bovine Recombinant Protein His Tag |
PROTP98072-1 |
BosterBio |
Regular: 100IU |
EUR 524 |
Description: Enterokinase Bovine Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 2428.0kDa.;The Enterokinase Bovine is purified by proprietary chromatographic techniques. |
RELM-Alpha Mouse Recombinant Protein, His Tag |
PROTQ9EP95-1 |
BosterBio |
Regular: 25ug |
EUR 317 |
Description: RELM-alpha Mouse Recombinant is manufactured with a signal sequence of phage fd (20aa) and C-terminal fusion of flagTag (10aa). The RELM-alpha Flag-Tagged Fusion Protein is a 13.3 kDa protein containing 91 amino acid residues with 30 additional amino acid residues - signal sequence of phage fd, flagTag (underlined). |
Human, Nanog Human Recombinant Protein, His Tag |
PROTQ9H9S0-1 |
BosterBio |
Regular: 20ug |
EUR 317 |
Description: NANOG Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 174 amino acids (1-154) and having a molecular mass of 19.6 kDa.;The NANOG is fused to a 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques. |
Human, Otoraplin Human Recombinant Protein, His Tag |
PROTQ9NRC9-1 |
BosterBio |
Regular: 20ug |
EUR 317 |
Description: OTOR Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 128 amino acids (26-128 a.a) and having a molecular mass of 14.3kDa. OTOR is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
Human, AITRL Human Recombinant Protein, His Tag |
PROTQ9UNG2-1 |
BosterBio |
Regular: 20ug |
EUR 317 |
Description: AITRL Recombinant Human produced in E.Coli is a single, non-glycosylated polypeptide chain (aa 50-177) containing a total of 137 amino acids and having a molecular mass of 15.6kDa. The AITRL protein is fused to a 9 aa His Tag at C-terminus and purified by proprietary chromatographic techniques. |
Human, Prolactin Human Recombinant Protein,His Tag |
PROTP01236-1 |
BosterBio |
Regular: 20ug |
EUR 317 |
Description: Prolactin-His Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 199 amino acids fragment (29-227) and having a molecular mass of 23 kDa with an amino-terminal hexahistidine tag. ;The Prolactin is purified by proprietary chromatographic techniques. |
Cyclophilin-B Human Recombinant Protein, His Tag |
PROTP23284-1 |
BosterBio |
Regular: 10ug |
EUR 317 |
Description: Cyclophilin-B Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain (Asp34-Glu216) containing 193 amino acids including a 10 aa His tag at N-terminus. The total calculated molecular mass is 22kDa. |
Human, CD95 Human Recombinant Protein, His Tag |
PROTP25445-1 |
BosterBio |
Regular: 20ug |
EUR 317 |
Description: Recombinant FAS antigen/ CD95 purified from E. coli is a single non-glycosilated polypeptide chain containing amino acids 157-320 of Fas antigen (base pairs 713-1190 of cDNA sequence). The recombinant CD95 is fused to C-terminal 6-histidine amino acids.;The FAS antigen is purified by proprietary chromatographic techniques. |
Recombinant HIV-1 Gag Protein [His] |
VAng-Lsx0260-100g |
Creative Biolabs |
100 µg |
EUR 594 |
Description: Recombinant HIV-1 Gag Protein, C-terminal 6xHis tagged, purified from E.coli. |
Recombinant HIV-1 p24 Protein [His] |
VAng-0527Lsx-inquire |
Creative Biolabs |
inquire |
Ask for price |
Description: HIV type 1 P24 Antigen, recombinant protein from insect cell expression system. |
Recombinant HIV-1 gp41 Protein [His] |
VAng-0529Lsx-inquire |
Creative Biolabs |
inquire |
Ask for price |
Description: HIV type 1 gp41 Antigen, recombinant protein from E. coli, MW 18.648 Da, 1.83 mg/mL. |
HIV-1 Tat Protein Peptide |
B1433-1 |
ApexBio |
1 mg |
EUR 128 |
Description: HIV-1 Tat Protein Peptide |
Recombinant Human HIV-1 (group M, subA, HXB2) Envelope gp160 Protein, His-SUMO, E.coli-100ug |
QP7356-ec-100ug |
EnQuireBio |
100ug |
EUR 408 |
Recombinant Human HIV-1 (group M, subA, HXB2) Envelope gp160 Protein, His-SUMO, E.coli-10ug |
QP7356-ec-10ug |
EnQuireBio |
10ug |
EUR 200 |
Recombinant Human HIV-1 (group M, subA, HXB2) Envelope gp160 Protein, His-SUMO, E.coli-1mg |
QP7356-ec-1mg |
EnQuireBio |
1mg |
EUR 1632 |
Recombinant Human HIV-1 (group M, subA, HXB2) Envelope gp160 Protein, His-SUMO, E.coli-200ug |
QP7356-ec-200ug |
EnQuireBio |
200ug |
EUR 634 |
Recombinant Human HIV-1 (group M, subA, HXB2) Envelope gp160 Protein, His-SUMO, E.coli-500ug |
QP7356-ec-500ug |
EnQuireBio |
500ug |
EUR 1060 |
Recombinant Human HIV-1 (group M, subA, HXB2) Envelope gp160 Protein, His-SUMO, E.coli-50ug |
QP7356-ec-50ug |
EnQuireBio |
50ug |
EUR 263 |
SUMO1 Small Ubiquitin-Related Modifier 1 Human Recombinant Protein, His Tag |
PROTP63165-1 |
BosterBio |
Regular: 20ug |
EUR 317 |
Description: SUMO1 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 109 amino acids (1-101) and having a molecular mass of 12.6 kDa.;SUMO1 is fused to a 8 amino acid His-tag at C-terminus & purified by proprietary chromatographic techniques. |
IL1F10 Interleukin 1 Family, Member 10 Human Recombinant Protein, His Tag |
PROTQ8WWZ1-1 |
BosterBio |
Regular: 20ug |
EUR 317 |
Description: IL1F10 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 172 amino acids (1-152) and having a molecular mass of 19.1kDa. |
IL-1RA Interleukin-1 Receptor Antagonist Human Recombinant Protein, His Tag |
PROTP18510-1 |
BosterBio |
Regular: 50ug |
EUR 682 |
Description: IL1Ra Human Recombinant produced in E.Coli is single, a non-glycosylated, Polypeptide chain containing 152 amino acids fragment (26-177) and having a total molecular mass of 21.63kDa with an amino-terminal hexahistidine tag. ;The IL-1Ra His is purified by proprietary chromatographic techniques. |
Human, Lymphotactin Human Recombinant Protein (XCL1), His Tag |
PROTP47992-1 |
BosterBio |
Regular: 10ug |
EUR 317 |
Description: XCL1 Human Recombinant produced in E.Coli is a single,non-glycosylated, polypeptide chain containing 114 amino acids (22-114 a.a.) and having a molecular mass of 12.5 kDa. The XCL1 is fused to a 20 amino acid His Tag at N-terminus and purified by proprietary chromatographic techniques. |
Human, Eotaxin Human Recombinant Protein (CCL11), His Tag |
PROTP51671-1 |
BosterBio |
Regular: 20ug |
EUR 317 |
Description: Eotaxin His Tag Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 74 amino acids fragment (24-87) corresponding to the mature Eotaxin protein and having a molecular mass of 8345.9 Dalton with an amino-terminal hexahistidine tag.;The Eotaxin-His is purified by proprietary chromatographic techniques. |
Human, GroES (HSP10) Human Recombinant Protein, His Tag |
PROTP61604-1 |
BosterBio |
Regular: 10ug |
EUR 317 |
Description: GroES His Protein is 12.0 kDa protein containing 111 amino acid residues of the GroES Human and the 10 aa N-Terminal His-tag. |
Human, Fractalkine Human Recombinant Protein (CX3CL1), His Tag |
PROTP78423-1 |
BosterBio |
Regular: 10ug |
EUR 317 |
Description: Fractalkine Human Recombinant fused with a 20 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 97 amino acids (25-100 a.a.) and having a molecular mass of 10.9kDa. ;The Fractalkine is purified by proprietary chromatographic techniques. |
EPGN Human, Epigen Human Recombinant Protein, His Tag |
PROTQ6UW88-1 |
BosterBio |
Regular: 20ug |
EUR 317 |
Description: EPGN Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 111 amino acids (23-110 a.a) and having a molecular mass of 12.1kDa. |
GRO-Gamma Mouse Recombinant Protein (CXCL3), His Tag |
PROTQ6W5C0-1 |
BosterBio |
Regular: 10ug |
EUR 317 |
Description: GRO-g Mouse Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 98 amino acids (28-100 a.a.) and having a molecular mass of 10.6kDa.;CXCL3 is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
Human, BRAK Human Recombinant Protein (CXCL14), His-Tag |
PROTO95715-1 |
BosterBio |
Regular: 5ug |
EUR 317 |
Description: CXCL14 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 88 amino acids and having a molecular mass of 10.66 kDa. ;The Human BRAK contains a 10 a.a. fusion His tag at N-Terminus. ;The BRAK is purified by proprietary chromatographic techniques. |
IP-10 Human Recombinant Protein (CXCL10), His Tag |
PROTP02778-1 |
BosterBio |
Regular: 25ug |
EUR 317 |
Description: IP-10 His Tag Human Recombinant ?produced in E.Coli is single, a non-glycosylated, Polypeptide chain containing 77 amino acids fragment (22-98) and having a total molecular mass of 8.5 kDa with an amino-terminal hexahistidine tag. ;The IP-10 His is purified by proprietary chromatographic techniques. |
SCGB1A1 Human, Uteroglobin Human Recombinant Protein, His Tag |
PROTP11684-1 |
BosterBio |
Regular: 10ug |
EUR 317 |
Description: Uteroglobin Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 80 amino acids and including a 10 a.a N-terminal His tag. The total molecular mass is 9.2kDa (calculated). |
Human, Rantes Human Recombinant Protein (CCL5), His Tag |
PROTP13501-1 |
BosterBio |
Regular: 10ug |
EUR 317 |
Description: Rantes Human Recombinant produced in E.Coli is single, a non-glycosylated, Polypeptide chain containing 68 amino acids fragment (24-91) having a total molecular mass of 17.5kDa and fused with a 4.5kDa amino-terminal hexahistidine tag.;The Rantes His is purified by proprietary chromatographic techniques. |
GRO-Beta Human Recombinant Protein (CXCL2), His Tag |
PROTP19875-1 |
BosterBio |
Regular: 10ug |
EUR 317 |
Description: GRO-Beta Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 94 amino acids and having a molecular mass of 10.1 kDa. ;The GRO-b is fused to 20 amino acid His Tag at N-terminus and purified by proprietary chromatographic techniques. |
GST, Glutathione S-Transferase Recombinant Protein, His Tag |
PROTP26624-1 |
BosterBio |
Regular: 50ug |
EUR 317 |
Description: Recombinant Schistosoma japonicum GST full length protein contains 244 amino acids(1-224 a.a.) expressed in E.coli, having a molecular mass of 28.3kDa. ;The GST protein is fused to a 20 amino acids His-Tag at N-terminus. ;The GST protein is purified by proprietary chromatographic techniques. |
EREG Human, Epiregulin Human Recombinant Protein, His Tag |
PROTO14944-1 |
BosterBio |
Regular: 25ug |
EUR 317 |
Description: EREG Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 69 amino acids (63-108 a.a) and having a molecular mass of 7.7kDa. EREG is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
Recombinant (HEK) HIV-1 gp120 (CN244, 36-511-aa, His-tag, 54 kda, |
RP-1630 |
Alpha Diagnostics |
25 ug |
EUR 408 |
Recombinant (HEK) HIV-1 gp120 (CN54, 27-498-aa, His-tag, 54 kda, |
RP-1631 |
Alpha Diagnostics |
25 ug |
EUR 408 |
Amphibian pores and skin is a wealthy supply of protection peptides with antiviral exercise. Here, we characterised a lectin-like peptide, fejerlectin (RLCYMVLPCP), remoted from the pores and skin of the frog Fejervarya limnocharis. Fejerlectin confirmed important hemagglutination and d-(+)-galacturonic acid-binding actions. Furthermore, fejerlectin suppressed the early entry of HIV-1 into goal cells by binding to the N-terminal heptad repeat of HIV-1 gp41 and stopping 6-HB formation and Env-mediated membrane fusion. Fejerlectin is the smallest lectin-like peptide recognized to date and represents a new and promising platform for anti-HIV-1 drug growth.